Author/Authors :
Batoux، نويسنده , , Nathalie and Benhaddou-Zerrouki، نويسنده , , Rachida and Bressolier، نويسنده , , Philippe and Granet، نويسنده , , Robert and Laumont، نويسنده , , Géraldine and Aubertin، نويسنده , , Anne-Marie and Krausz، نويسنده , , Pierre، نويسنده ,
Abstract :
The cross metathesis of 3′-allylic analogues of thymidine, 2′-deoxyuridine and 2′-deoxycytidine is used to obtain nucleoside dimers, in which an unsaturated hydrocarbon chain links the 3′ positions of the sugar moieties. The biological activity on HIV infected cells was also evaluated.