Reactions of 4,4′-difluoro-biphenyl-3,3′-dicarboxylic acid dimethyl ester with amino alcohols. A convenient route to biphenyl tetra-alcohols

An efficient method for the preparation of biphenyl tetraols 10–15 and 18 is described. These poly-functional products should prove valuable as scaffolds for combinatorial library construction and as core structural units for dendrimer synthesis.