Title of article :
Synthesis of spongian diterpenes: (−)-spongian-16-oxo-17-al and (−)-acetyldendrillol-1
Author/Authors :
Arn?، نويسنده , , Manuel A. Gonzalez، نويسنده , , Miguel A and Mar??n، نويسنده , , M.Luisa and Zaragoz?، نويسنده , , Ram?n J، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
An efficient diastereoselective synthesis of the spongian diterpenes (−)-spongian-16-oxo-17-al (1) and (−)-acetyldendrillol-1 (13) is described starting from (+)-podocarp-8(14)-13-one (6) via the ester-dialdehyde 11 as key intermediate. The absolute configuration at C-17 in synthetic compound 13 has conclusively been proved by NOE experiments.
Keywords :
Diterpenes , Synthesis , Sponges , podocarpenone , Marine metabolites
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
