Author/Authors :
Guo، نويسنده , , Zhenrong and Dowdy، نويسنده , , Eric D and Li، نويسنده , , Wen-Sen and Polniaszek، نويسنده , , Richard and Delaney، نويسنده , , Edward، نويسنده ,
Abstract :
The selective monoamidation of diesters and amidation of esters mediated by Lewis acids are described. The selective amidations of dimethyl pyridine-2,5-dicarboxylate (1) and dimethyl 2,3-indole-dicarboxylate (4) with primary and secondary amines mediated by MgCl2 or MgBr2 under mild conditions gave the corresponding ester-amides in high yield.
