• Title of article

    2-Polystyrylsulfonyl ethanol supports for the solid-phase syntheses of hydantoins and ureas

  • Author/Authors

    Huang، نويسنده , , Wenqiang and Cheng، نويسنده , , Shaoling and Sun، نويسنده , , Weimin، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2001
  • Pages
    2
  • From page
    1973
  • To page
    1974
  • Abstract
    Reaction of sodium polystyrylsulfinate 1 with 2-chloroethanol gave the 2-arylsulfonyl ethanol resin 2, which was converted to the polymer-supported amine 5. Amine 5 was coupled with an isocyanate or an isothiocyanate to give the polymer-supported urea derivatives 6. Treatment of the resin 6 with 6N HCl gave hydantoins 7, while reaction of the same resin with 4N NaOH then HCl gave the urea derivatives 8.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2001
  • Journal title
    Tetrahedron Letters
  • Record number

    1643642