• Title of article

    Parallel modification of tropane alkaloids

  • Author/Authors

    Aberle، نويسنده , , Nicholas S and Ganesan، نويسنده , , A and Lambert، نويسنده , , John N and Saubern، نويسنده , , Simon and Smith، نويسنده , , Reg، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2001
  • Pages
    3
  • From page
    1975
  • To page
    1977
  • Abstract
    Various tropane alkaloids have been prepared by structural modification of the readily available natural product, scopolamine 1. Reaction of isocyanates with 6,7-dehydrotropine 5 provided a number of urethanes 6a–e. Reductive amination of tropinone 7 and subsequent reaction with isocyanates provided ureas 9a–f. Mitsunobu inversion of the C-3 alcohol of tropine 10 afforded the epimeric ester 11.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2001
  • Journal title
    Tetrahedron Letters
  • Record number

    1643646