• Title of article

    Synthesis and characterization of flavin-tethered peptide nucleic acid

  • Author/Authors

    Ikeda، نويسنده , , Hisafumi and Yoshida، نويسنده , , Kohzo and Ozeki، نويسنده , , Makoto and Saito، نويسنده , , Isao، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2001
  • Pages
    3
  • From page
    2529
  • To page
    2531
  • Abstract
    We synthesized flavin-containing PNA monomer unit 5 from lumiflavin and prepared PNAs containing a flavin moiety (FPNA) by the standard tBoc chemistry. Each PNA oligomer was purified by reversed-phase HPLC and characterized by MALDI-TOF MS and UV spectra. Thermodynamic analyses indicated that the PNA oligomer containing a flavin moiety near the amino terminal considerably stabilized the PNA–DNA hybrids.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2001
  • Journal title
    Tetrahedron Letters
  • Record number

    1644008