• Title of article

    Solid-phase synthesis of peptide aldehydes directly on acetal resin

  • Author/Authors

    Yao، نويسنده , , Gong Wu and Xu، نويسنده , , Hong Yan، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2001
  • Pages
    4
  • From page
    2549
  • To page
    2552
  • Abstract
    A practical strategy for solid-phase synthesis of peptide aldehydes has been developed employing a 10,11-dihydroxyundecanoic acid (DHUA) functionalized resin. High loading levels are obtained for amino aldehydes as their respective acetals. After classical Fmoc SPPS, treatment of the derivatized resin with 95% TFA/H2O affords peptide aldehydes in high yield and purity.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2001
  • Journal title
    Tetrahedron Letters
  • Record number

    1644017

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1644017