Author/Authors :
Franck، نويسنده , , Xavier and Vaz Araujo، نويسنده , , Maria E and Jullian، نويسنده , , Jean-Christophe and Hocquemiller، نويسنده , , Reynald and Figadère، نويسنده , , Bruno، نويسنده ,
Abstract :
iso-Cladospolide B 1 was previously characterized from the fungal isolate I96S215 obtained from a marine sponge collected in Indonesia. However, neither the relative nor the absolute configurations were reported. We describe in this letter a synthetic pathway which allowed us to prepare 1 and attribute the absolute configurations of the three stereogenic centers.
Keywords :
structure determination , polyketides , marine fungi , Asymmetric aldol reaction
