Author/Authors :
Sato، نويسنده , , Masayuki and Nakashima، نويسنده , , Hiromi and Hanada، نويسنده , , Keisuke and Hayashi، نويسنده , , Masato and Honzumi، نويسنده , , Masatoshi and Taniguchi، نويسنده , , Takahiko and Ogasawara، نويسنده , , Kunio، نويسنده ,
Abstract :
Starting from enantiopure 4-cumyloxy-2-cyclopenten-1-one, a route to 5- and 6-substituted hyropyran-2-ones has been developed. The method has achieved the synthesis of 4,5-cis- and 4,5-trans-5-ethyl-4-hydroxytetrahydropyran-2-ones assigned to marine natural products simplactones A and B to disprove the former and revise the latter of the proposed structures.
