Title of article :
Generation and reactions of 2,3-dilithio-N-methylindole. Synthesis of 2,3-disubstituted indoles
Author/Authors :
Liu، نويسنده , , Yanbing and Gribble، نويسنده , , Gordon W، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
Generation of 2,3-dilithio-N-methylindole (7) from 2,3-diiodo-N-methylindole (6) and subsequent reaction with various electrophiles (NH4Cl, DMF, ClCO2Me, CO2, phthalic anhydride) affords the corresponding 2,3-disubstituted indoles in good to excellent yields (41–99%).
Keywords :
2 , 2 , 3-dilithio-N-methylindole , 3-diiodo-N-methylindole , lithiation , 11-dione
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters