Title of article
α-Aminocyclopropanone hydrates: potential transition-state analog inhibitors of serine proteases
Author/Authors
Doris ، نويسنده , , Eric and Wagner، نويسنده , , Alain and Mioskowski، نويسنده , , Charles، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
3183
To page
3185
Abstract
The synthesis of two α-aminocyclopropanone hydrates is reported. These synthons could find biological applications by acting as transition-state analog inhibitors of hydrolytic enzymes, such as serine proteases.
Keywords
Cyclopropanation , Enzyme inhibitors , cyclopropanones
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1644568
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