Title of article
Synthesis of 4-demethoxyadriamycinone utilizing ruthenium-catalyzed oxidation of allyl acetates
Author/Authors
Hottop، نويسنده , , Torsten and Gutke، نويسنده , , Hans-Jürgen and Murahashi، نويسنده , , Shun-Ichi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
4
From page
3343
To page
3346
Abstract
A new method for the construction of the side chain of anti-cancer drugs adriamycins is demonstrated by the synthesis of 4-demethoxyadriamycinone. The key step is the ruthenium-catalyzed oxidation of allyl acetates to the corresponding α-hydroxyketones.
Keywords
ruthenium-catalyzed oxidation , 4-demethoxyadriamycinone , anthracyclinone , ?-ketol
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1644674
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