Title of article
Novel and efficient transformation of α-amino nitrile to α-imino and α-amide nitriles in asymmetric Strecker synthesis
Author/Authors
Namba، نويسنده , , Kosuke and Kawasaki، نويسنده , , Masanori and Takada، نويسنده , , Ichinori and Iwama، نويسنده , , Seiji and Izumida، نويسنده , , Masashi and Shinada، نويسنده , , Tetsuro and Ohfune، نويسنده , , Yasufumi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
4
From page
3733
To page
3736
Abstract
Oxidation of α-amino nitrile 4 with ozone gave rise to a mixture of α-imino nitrile 5 and a novel fragmentation product of 6 in one-step. The mixture was converted to a variety of α-substituted α-amino acids 7 in high yields, which enabled the asymmetric transferring Strecker synthesis to be a widely useful method.
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1644982
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