Author/Authors :
Schell، نويسنده , , Peter and Orgueira، نويسنده , , Hernan A and Roehrig، نويسنده , , Susanne and Seeberger، نويسنده , , Peter H، نويسنده ,
Abstract :
d-Glucuronic acid glycals can be efficiently synthesized from diacetone glucose or tri-O-acetyl glycal and can be transformed into d-glucuronic acid donors and acceptors in high yields. Base catalyzed epimerization of d-glucuronic acid glycals provides access to the corresponding l-iduronic acid glycals. Both d-glucuronic and l-iduronic acid glycals were transformed into glycosylating agents for use in the synthesis of glycosaminoglycan oligosaccharides.
