Title of article
Improved yields of meta-amination and symmetrical and unsymmetrical diamination of benzenes
Author/Authors
Brown، نويسنده , , George R and Foubister، نويسنده , , Alan J and Roberts، نويسنده , , Craig A and Wells، نويسنده , , Stuart L and Wood، نويسنده , , Robin، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
3917
To page
3919
Abstract
Much higher yields were found after shorter reaction times for the meta-substituted amination of benzenes in DMPU with microwave heating in a sealed tube (180°C, 5 h), e.g. piperidine and m-fluorobenzonitrile 1 gave the m-substituted 3 in 92% yield. These modified reaction conditions also afforded a new synthesis of unsymmetrical diamines in >80% yield.
Keywords
amination , aryl halides , substituent effects
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1645125
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