Title of article :
Grob-type fragmentation of N-alkyl-2-cyano-5-bromopiperidines to unsaturated imidoyl cyanides
Author/Authors :
Erick Rosas-Alonso، نويسنده , , Erick and Abbaspour Tehrani، نويسنده , , Kourosch and Boelens، نويسنده , , Mark A. Knight، نويسنده , , David W and Yu، نويسنده , , Valentina and De Kimpe، نويسنده , , Norbert، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
2-Cyano-5-bromopiperidines, derived from the stereoselective addition of cyanide to 5-bromomethyl-1-pyrrolinium salts, underwent a Grob fragmentation by reaction with sodium hydride in dimethylformamide, affording unsaturated imidoyl cyanides.
Keywords :
cyclization , Ring opening , piperidines , Grob fragmentation , ?-iminonitriles , imidoyl cyanides
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
