Author/Authors :
Ohta، نويسنده , , Emi and Ohta، نويسنده , , Shinji and Kubota، نويسنده , , Natsuki K and Suzuki، نويسنده , , Makoto and Ogawa، نويسنده , , Tatsuhiro and Yamasaki، نويسنده , , Akiko and Ikegami، نويسنده , , Susumu، نويسنده ,
Abstract :
A new macrolide, micromonospolide A, was isolated from an undescribed actinomycete, Micromonospora sp., and its structure was elucidated to be a bafilomycin-type macrolide which has a 16-membered lactone ring on the basis of spectroscopic data. Micromonospolide A inhibited gastrulation of starfish embryos at a concentration of 10 ng/ml or greater.
Keywords :
Macrolides , Microorganisms , natural products , Biologically active compounds
