One-pot, new stereoselective synthesis of endo-tropanamine
Author/Authors :
Allegretti، نويسنده , , Marcello and Berdini، نويسنده , , Valerio and Cesta، نويسنده , , M.Candida and Curti، نويسنده , , Roberto and Nicolini، نويسنده , , Luca and Topai، نويسنده , , Alessandra، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Pages :
3
From page :
4257
To page :
4259
Abstract :
A palladium-catalysed reduction of ketones to primary amines by reaction with ammonium formate in aqueous methanol is described. The proposed method provides a one-pot synthesis of 3-endo-tropanamine in high yields and stereoselectivity.
