Title of article
Catalytic enantioselective direct Michael additions of ketones to alkylidene malonates
Author/Authors
Betancort، نويسنده , , Juan M and Sakthivel، نويسنده , , Kandasamy and Thayumanavan، نويسنده , , Rajeswari and Barbas III، نويسنده , , Carlos F، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
4
From page
4441
To page
4444
Abstract
Enantioselective direct Michael additions of ketones using (S)-1-(2-pyrrolidinylmethyl)-pyrrolidine as a catalyst are described. Michael adducts with up to 91% e.e. were obtained by the reaction of alkylidene malonates with simple unactivated ketones under mild reaction conditions.
Keywords
asymmetric catalyst , Michael reaction , asymmetric synthesis
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1645552
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