Title of article :
Mild chemo-enzymatic synthesis of polymer-supported cinchona alkaloids and their application in asymmetric Michael addition
Author/Authors :
Athawale، نويسنده , , Vilas and Manjrekar، نويسنده , , Narendra، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
Cinchona alkaloid (CA) monomers were synthesised enzymatically in high yield (90%) by selectively acrylating the primary -OH group of the CA, and the co-polymers obtained with acrylonitrile were tested for their efficiency for asymmetric induction in Michael addition reactions.
Keywords :
Lipase , Chemo-enzymatic synthesis , Cinchona alkaloid , Polymer-supported catalyst
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
