Title of article
Diastereocontrolled reduction of cyclic β-enaminones. A new diastereoselective route to 2,6-disubstituted piperidines
Author/Authors
Fréville، نويسنده , , Stéphanie and Delbecq، نويسنده , , Philippe and Thuy، نويسنده , , Vu Moc and Petit، نويسنده , , Huguette and Célérier، نويسنده , , Jean Pierre and Lhommet، نويسنده , , Gérard، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
4609
To page
4611
Abstract
A new diastereoselective synthesis of 2,6-disubstituted piperidinic alkaloids is presented. Three natural compounds, the (−)-pinidinone 1a, the (+)-dihydropinidine 1b and the (−)-pinidinol 1c were prepared from optically pure (6R)-6-methylpiperidin-2-one 2. This method is based on the chemo- and diastereocontrolled reductions of an exocyclic β-enamino ketone.
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1645687
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