• Title of article

    Synthesis of (4R*,5R*)-4-acetylamino-5-diethylcarbamoylcyclohex-1-ene-1-carboxylic acid and (3R*,4R*)-4-acetylamino-3-diethylcarbamoylcyclohex-1-ene-1-carboxylic acid: new inhibitors of influenza virus sialidases

  • Author/Authors

    Kerrigan، نويسنده , , Sean A and Smith، نويسنده , , Paul W and Stoodley، نويسنده , , Richard J، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2001
  • Pages
    4
  • From page
    4709
  • To page
    4712
  • Abstract
    (4R*,5R*)-4-Acetylamino-5-diethylcarbamoylcyclohex-1-ene-1-carboxylic acid and (3R*,4R*)-4-acetylamino-3-diethylcarbamoylcyclohex-1-ene-1-carboxylic acid have been synthesised using a Diels–Alder tactic; both compounds are selective inhibitors of influenza A sialidase, the latter compound being particularly potent.
  • Keywords
    antivirals , cyclohexenes , Diels–Alder reactions , Nitro compounds , regioselection , dehydration
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2001
  • Journal title
    Tetrahedron Letters
  • Record number

    1645767

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1645767