Title of article
Diastereoselective Michael reactions of (1R)-(+)-camphor methyl ketone enolates with nitro olefins
Author/Authors
Palomo، نويسنده , , Claudio and Aizpurua، نويسنده , , Jes?s M and Oiarbide، نويسنده , , M and Garc??a، نويسنده , , Jes?s M and Gonz?lez، نويسنده , , Alberto and Odriozola، نويسنده , , I and Linden، نويسنده , , Anthony، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
4829
To page
4831
Abstract
The reaction of the sodium enolate of the methyl ketone 2 with a range of nitro olefins proceeds readily to give the corresponding Michael adducts in good yields and diastereoselectivities. Subsequent oxidative cleavage of the acyloin moiety provides γ-nitroalkanoic acids along with (1R)-(+)-camphor, the chiral auxiliary of the process, which can be recovered and reused.
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1645857
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