Author/Authors :
Mino، نويسنده , , Takashi and Hata، نويسنده , , Sosuke and Ohtaka، نويسنده , , Kouji and Sakamoto، نويسنده , , Masami and Fujita، نويسنده , , Tsutomu، نويسنده ,
Abstract :
Palladium-catalyzed asymmetric allylic alkylation of 1,3-diphenyl-2-propenyl acetate (8a) with a dimethyl malonate–BSA–LiOAc system has been successfully carried out in the presence of novel chiral phosphine–oxazinane ligands such as 5b in good yields with good enantioselectivities (up to 95% ee).
Keywords :
oxazinane , asymmetric synthesis , phosphine , PALLADIUM
