Title of article :
Synthesis of optically active aldol derivatives through chirality transfer type 1,2-Wittig rearrangement of α-alkoxycarboxamides
Author/Authors :
Kitagawa، نويسنده , , Osamu and Momose، نويسنده , , Shu-ichi and Yamada، نويسنده , , Yoichiro and Shiro، نويسنده , , Motoo and Taguchi، نويسنده , , Takeo، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
Treatment of chiral α-benzyloxy- or α-propargyloxycarboxamide with tert-BuLi gave β-hydroxycarboxamides (aldol derivatives) in high optical purity through the formation of α-lithiated ethers and the subsquent 1,2-Wittig rearrangement.
Keywords :
hydroxy acids and derivatives , Asymmetric reaction , Wittig rearrangement , aldols
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
