Title of article
An approach towards the C1–C16 fragment of antineoplastic macrolide bryostatins by kinetic resolution of a racemic terminal epoxide using Jacobsenʹs catalyst
Author/Authors
Yadav، نويسنده , , J.S and Bandyopadhyay، نويسنده , , A and Kunwar، نويسنده , , A.C، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
5
From page
4907
To page
4911
Abstract
A stereo- and enantioselective approach towards the C1–C16 fragment of bryostatins is reported using Jacobsenʹs catalyst for kinetic resolution of a terminal epoxide, a Horner–Wadsworth–Emmons coupling reaction and a 1,4-Michael type cyclization as key steps.
Keywords
bryostatins , Antitumour compounds , coupling reactions , Michael reactions
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1645903
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