Title of article
Titanium-mediated diastereoselective formation of (E)-2-alkyl-1-ethenylcyclopropanols from β-haloesters
Author/Authors
Sylvestre، نويسنده , , Isabelle Hourmand-Ollivier، نويسنده , , Jean and Salaün، نويسنده , , Jacques، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
4
From page
4991
To page
4994
Abstract
The titanium(IV)-mediated cyclopropanation of ethyl β-chloropropionate by Grignard reagents and in situ tosylation, followed by base-induced dehydrochlorination provided diastereoselectivity pure (E)-2-alkyl-1-ethenyl-1-(tosyloxy)cyclopropanes, suitable precursors of 1,1-ethyleneallylmetal species of significant synthetic potential.
Keywords
Dehydrohalogenation , (E)-2-alkyl-1-ethenylcyclopropanols , titanium-mediated cyclopropanations , sulfonic esters
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1645952
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