Author/Authors :
Fern?ndez، نويسنده , , Franco and Garc??a-Mera، نويسنده , , Xerardo and Enrique Rodr??guez-Borges، نويسنده , , José and Manuel Blanco، نويسنده , , José، نويسنده ,
Abstract :
A new, straitghtforward and efficient method for preparing (+)-8-phenylisomenthol 1 from its diastereomer (+)-8-phenylisoneomenthol 2 is described. Conversion of 2 to (+)-8-phenyl-2-menthene 5, followed by oxidation to the corresponding (+)-trans-epoxide 6 and reduction of 6 with LiBEt3H afforded 1 in 78% overall yield.