Title of article :
Novel syntheses of densely functionalized indolizines, di- and tetrahydroindolizines from 2-formyl-1,4-dihydropyridine systems based on cascade process
Author/Authors :
Stefan Marchalin، نويسنده , , ?tefan and Cvopov?، نويسنده , , Katar??na and Pham-Huu، نويسنده , , Duy-Phong and Chud??k، نويسنده , , Miloslav and Kozisek، نويسنده , , Jozef and Svoboda، نويسنده , , Ingrid and Da??ch، نويسنده , , Adam، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
Several indolizines, di- and tetrahydroindolizines have been synthesized successfully in a one-pot procedure, in two or three steps from 2-formyl-1,4-dihydropyridine derivatives and malonitrile in 57–87% yield. The general mechanism leading to these azacyclic compounds, involving 2-dicyanovinyl-1,4-dihydropyridines, is discussed.
Keywords :
Cascade process , Tetrahydroindolizines , Indolizines , dihydropyidines (DHP) , dihydroindolizines , stereoselectivity
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters