Ring expansion: formal total synthesis of (−)-paroxetine
Author/Authors :
Cossy، نويسنده , , Janine and Mirguet، نويسنده , , Olivier and Gomez Pardo، نويسنده , , Domingo and Desmurs، نويسنده , , Jean-Roger، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Pages :
3
From page :
5705
To page :
5707
Abstract :
A ring expansion and a radical dehalogenation have been used as the key steps in a formal total synthesis of (−)-paroxetine. A stereoselective ring expansion of prolinol generated the substituted piperidine ring precursor of (−)-paroxetine.
