Title of article :
Preparation of polyfunctional pyridines by a palladium(0)-catalyzed cross-coupling of functionalized aryl Grignard reagents
Author/Authors :
Bonnet، نويسنده , , Véronique and Mongin، نويسنده , , Florence and Trécourt، نويسنده , , Francois and Quéguiner، نويسنده , , Guy and Knochel، نويسنده , , Paul، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Pages :
3
From page :
5717
To page :
5719
Abstract :
Difunctionalized pyridines can be prepared by a Pd(0)-catalyzed cross-coupling of functionalized arylmagnesium compounds with chloro- or bromopyridines at temperatures as low as −40°C. An addition–elimination mechanism involving a palladate intermediate is proposed.
Keywords :
palladium-catalysis , pyridine synthesis , functionalized organomagnesium reagent , heterocycle synthesis
Journal title :
Tetrahedron Letters
Serial Year :
2001
Journal title :
Tetrahedron Letters
Record number :
1646506
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1646506
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