Title of article
An efficient one-pot synthesis of N-alkyl carbamates from primary amines using Cs2CO3
Author/Authors
Salvatore، نويسنده , , Ralph Nicholas and Ledger، نويسنده , , Jeremy A and Jung، نويسنده , , Kyung Woon، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
6023
To page
6025
Abstract
A facile one-pot synthesis of N-alkyl carbamates is described. A primary amine, CO2, and an alkyl halide underwent a three-component coupling using cesium carbonate and tetrabutylammonium iodide (TBAI) giving rise to the resultant carbamate. In the presence of Cs2CO3, subsequent N-alkylation of the in situ generated carbamate with a different alkyl halide afforded various aliphatic N-alkyl carbamates, respectively.
Keywords
Carbamate , N-Alkylation , cesium carbonate
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1646729
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