• Title of article

    An efficient one-pot synthesis of N-alkyl carbamates from primary amines using Cs2CO3

  • Author/Authors

    Salvatore، نويسنده , , Ralph Nicholas and Ledger، نويسنده , , Jeremy A and Jung، نويسنده , , Kyung Woon، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2001
  • Pages
    3
  • From page
    6023
  • To page
    6025
  • Abstract
    A facile one-pot synthesis of N-alkyl carbamates is described. A primary amine, CO2, and an alkyl halide underwent a three-component coupling using cesium carbonate and tetrabutylammonium iodide (TBAI) giving rise to the resultant carbamate. In the presence of Cs2CO3, subsequent N-alkylation of the in situ generated carbamate with a different alkyl halide afforded various aliphatic N-alkyl carbamates, respectively.
  • Keywords
    Carbamate , N-Alkylation , cesium carbonate
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2001
  • Journal title
    Tetrahedron Letters
  • Record number

    1646729