Title of article :
Regioselectivity of Pictet–Spengler cyclization: synthesis of halotetrahydroisoquinolines
Author/Authors :
Cho، نويسنده , , Su-Dong and Song، نويسنده , , Sang-Yong and Hur، نويسنده , , Eun-Joo and Chen، نويسنده , , Ma and Joo، نويسنده , , Woo-Hong and Falck، نويسنده , , J.R and Yoon، نويسنده , , Yong-Jin and Shin، نويسنده , , Dong-Soo، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Pages :
3
From page :
6251
To page :
6253
Abstract :
The regioselectivity of the Pictet–Spengler cyclization for the synthesis of isoquinolines depends on the aryl substituent at C-2. The ratio of halotetrahydroisoquinoline 4 to isoquinoline 3 increases with increasing electrophilicity of the aromatic ring (H≪I<Br<Cl).
Keywords :
halotetrahydroisoquinoline , Pictet–Spengler , Condensation , cyclization
Journal title :
Tetrahedron Letters
Serial Year :
2001
Journal title :
Tetrahedron Letters
Record number :
1646899
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1646899
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