Author/Authors :
Leung، نويسنده , , DAVID B. and ATKINS، نويسنده , , Joshua H and Breslow، نويسنده , , Ronald، نويسنده ,
Abstract :
A series of cyclodextrin trimers and dimers were prepared and examined as binders for appropriate trimeric and dimeric aminoacid amides. Tritopic binding was stronger than ditopic binding, although the free energies were not strictly additive. Such trimers are attractive prospects for the binding of polypeptides and proteins.