Title of article :
P(RNCH2CH2)3N-catalyzed diastereoselective synthesis of oxazolines
Author/Authors :
Kisanga، نويسنده , , Philip and Ilankumaran، نويسنده , , Palanichamy and Verkade، نويسنده , , John G، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
We report herein that the strong nonionic bases P(RNCH2CH2)3N(R=Me, 1a; i-Pr, 1b) catalyze the diastereoselective synthesis of thirteen oxazolines in the presence of 5–30% of these catalysts. The formation of the oxazolines proceeds under very mild conditions in good to excellent yields with high diastereoselectivity (>95:5) for the trans isomer.
Keywords :
Oxazolines , Catalysts , proazaphosphatranes , diastereoselectivity , nonionic base
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
