• Title of article

    Stereoselective synthesis of β-linked TBDMS-protected chitobiose-asparagine: a versatile building block for amyloidogenic glycopeptides

  • Author/Authors

    Wendolin Bosques، نويسنده , , Carlos J and Tai، نويسنده , , Vincent W.-F and Imperiali، نويسنده , , Barbara، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2001
  • Pages
    4
  • From page
    7207
  • To page
    7210
  • Abstract
    A simple and efficient synthesis of a Fmoc-l-Asn[β-chitobiose(TBDMS)5]-OH with selectivity for the β-linked carbohydrate is described. The utility of this building block is illustrated in the synthesis of a glycosylated amyloidogenic peptide representing the 175-195††Human sequence numbering is used for the mouse PrPGP. ent of the mouse prion protein (PrPGP).
  • Keywords
    glycopeptide synthesis , amyloidogenic peptide , protein glycosylation
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2001
  • Journal title
    Tetrahedron Letters
  • Record number

    1647566

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1647566