Title of article :
Facile construction of 6-carbomethoxymethyl-3-methoxy-1,2-dioxane, a core structure of spongean anti-malarial peroxides
Author/Authors :
Murakami، نويسنده , , Nobutoshi and Kawanishi، نويسنده , , Motoyuki and Itagaki، نويسنده , , Sawako and Horii، نويسنده , , Toshihiro and Kobayashi، نويسنده , , Motomasa، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
Facile construction of 6-carbomethoxymethyl-3-methoxy-1,2-dioxane, the core structure of spongean anti-malarial peroxides, has been developed by combination of Sc(OTf)3-mediated peroxyhemiacetalization of keto-ester and Michael addition of the resultant peroxyhemiacetal in the fluorinated alcohol.
Keywords :
anti-malarials , peroxyhemiacetal , Michael addition , Marine metabolites , Peroxides
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
