Author/Authors :
Kobayashi، نويسنده , , Sh? and Shiraishi، نويسنده , , Nobuyuki and Lam، نويسنده , , William W.-L and Manabe، نويسنده , , Kei، نويسنده ,
Abstract :
The first synthesis of an optically active 1-phenylphospholane-2-carboxylic acid–borane complex and a 1-phenylphosphorinane-2-carboxylic acid–borane complex, which are proline and pipecolic acid phosphorous analogues, has been accomplished. The key to the synthesis is the enantioselective deprotonation accompanied with diastereoselective carboxylation.
