Author/Authors :
Hansen، نويسنده , , Karl B and Springfield، نويسنده , , Shawn A and Desmond، نويسنده , , Richard and Devine، نويسنده , , Paul N and Grabowski، نويسنده , , Edward J.J and Reider، نويسنده , , Paul J، نويسنده ,
Abstract :
Reaction of 1-N-alkyl triazoles with an alkyl radical generated from the corresponding carboxylic acid, affords the triazole ring alkylated selectively in the 5 position. Secondary radicals perform best in the intermolecular reaction, while primary radicals alkylate the triazole in an intramolecular fashion.