Enantioselective syntheses of (+)-decursinol and (+)-trans-decursidinol

Selective and practical asymmetric syntheses of (+)-decursinol (1) and (+)-trans-decursidinol (2) have been achieved using naturally occurring umbelliferone, demethylsuberosin, and xanthyletin as the synthetic intermediates. The absolute stereochemistry was established in the late stage of synthesis by employing Jacobsenʹs enantioselective epoxidation conditions.