Title of article
Preparation of a resin-bound cyclic malonic ester and a facile solid-phase synthesis of 4(1H)quinolones
Author/Authors
Huang، نويسنده , , Xian and Liu، نويسنده , , Zhanxiang، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
7655
To page
7657
Abstract
A resin-bound cyclic malonic ester has been prepared on Merrifield resin. Reaction of the cyclic malonic ester with triethyl orthoformate and subsequent substitution by an arylamine afforded arylaminomethylene cyclic malonic ester preloaded resin. A series of 4(1H)quinolones were prepared by thermal cyclization in moderate yields and high purity.
Keywords
solid-phase synthesis , Meldrumיs acid , cyclic malonic ester , 4(1H)quinolone
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1647911
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