Title of article :
Catalytic enantioselective synthesis of a novel inhibitor of ceramide trafficking, (1R,3R)-N-(3-hydroxy-1-hydroxymethyl-3-phenylpropyl)dodecanamide (HPA-12)
Author/Authors :
Ueno، نويسنده , , Masaharu and Kitagawa، نويسنده , , Hidetoshi and Ishitani، نويسنده , , Haruro and Yasuda، نويسنده , , Satoshi and Hanada، نويسنده , , Kentaro and Kobayashi، نويسنده , , Sh?، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
A novel inhibitor of ceramide trafficking, (1R,3R)-N-(3-hydroxy-1-hydroxymethyl-3-phenylpropyl)dodecanamide (HPA-12), has been synthesized using a chiral zirconium-catalyzed asymmetric Mannich-type reaction as a key-step.
Keywords :
HPA-12 , Mannich-type reaction , a novel inhibitor of ceramide trafficking , Asymmetric reaction
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
