• Title of article

    Acyl radical cyclisation onto pyrroles

  • Author/Authors

    Allin، نويسنده , , Steven M and Barton، نويسنده , , William R.S and Bowman، نويسنده , , W.Russell and McInally، نويسنده , , Tom، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2001
  • Pages
    4
  • From page
    7887
  • To page
    7890
  • Abstract
    Synthetically useful [1,2-a]-fused pyrroles, e.g. 2,3-dihydro-1H-pyrrolizidines substituted in the 1- and 7-positions, have been generated by acyl radical cyclisation onto pyrroles using N-(ω-acyl)-radicals generated from acyl-selenide precursors. The protocol does not require high pressures of CO. Mechanistic studies indicate the key role of azo radical initiators as oxidants of the intermediate π-radicals.
  • Keywords
    acyl selenides , Heteroarenes , acyl radicals , Radical cyclisation , tributyltin hydride
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2001
  • Journal title
    Tetrahedron Letters
  • Record number

    1647967