Title of article
Addition of silanethiols to aldehydes and ketones: a simple route to homochiral α-siloxyalkanethiols
Author/Authors
Cai، نويسنده , , Yudong and Roberts، نويسنده , , Brian P، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
4
From page
8235
To page
8238
Abstract
In the presence of imidazole as a catalyst, silanethiols R3SiSH react by addition with aldehydes and with ketones that carry electron-withdrawing substituents to give α-siloxyalkanethiols R1R2C(SH)OSiR3. Diastereoselective addition of a silanethiol to an enantiopure aldehyde or ketone provides a convenient route to a homochiral α-siloxyalkanethiol R1R2C*(SH)OSiR3.
Keywords
silicon and compounds , Aldehydes , Asymmetry , ketones , thiols
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1648136
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