Title of article :
A convenient synthesis of 2-fluoro- and 6-fluoro-(2S,3R)-threo-(3,4-dihydroxyphenyl)serine using Sharpless asymmetric aminohydroxylation
Author/Authors :
Kim، نويسنده , , In Ho and Kirk، نويسنده , , Kenneth L، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
Ring-fluorinated β-hydroxy α-amino methyl esters 3b,c were synthesized enantioselectively using Sharpless asymmetric aminohydroxylation. These were converted to 2-fluoro- and 6-fluoro-(2S,3R)-threo-(3,4-dihydroxyphenyl)serine 1b,c using our previously published procedure.
Keywords :
2-fluoro- and 6-fluoro-(2S , 3R)-threo-(3 , Sharpless asymmetric aminohydroxylation , 4-dihydroxyphenyl)serine , regioselectivity , Enantioselectivity
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
