A tandem decarboxylation/Diels–Alder reaction of 5-amino-1-phenyl-4-pyrazolecarboxylic acid with 1,3,5-triazines

A tandem decarboxylation/Diels–Alder reaction of 5-amino-1-phenyl-4-pyrazolecarboxylic acid with various 1,3,5-triazines was reported. The dienophile, 5-amino-1-phenylpyrazole, was generated in situ via decarboxylation and immediately trapped by 1,3,5-triazines leading to 4,6-disubstituted 1-phenylpyrazolo[3,4-d]pyrimidines in one step.