Author/Authors :
Lecouvey، نويسنده , , Marc and Mallard، نويسنده , , Isabelle and Bailly، نويسنده , , Théodorine and Burgada، نويسنده , , Ramon and Leroux، نويسنده , , Yves، نويسنده ,
Abstract :
A simple and efficient one-pot procedure for synthesis of 1-hydroxymethylene-1,1-bisphosphonic acids by reaction of acyl chlorides and tris(trimethylsilyl)phosphite is described. This method was applied to the synthesis of new phosphonated chelating tripod ligands.