Title of article :
Chemoselective reduction of pyrimidines. An access to enantiopure tetrahydropyrimidinones
Author/Authors :
Agami، نويسنده , , Claude and Dechoux، نويسنده , , Luc and Melaimi، نويسنده , , Mohand، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
A synthesis of substituted 1,3-tetrahydropyrimidinones 8 starting from homochiral synthon 2 is described. Chemoselective reduction of pyrimidines 4 using BH3·THF provides an access to regioselective N-protected tetrahydropyrimidinones 8.
Keywords :
1 , tetrahydropyrimidinones , chemoselective reduction , pyrimidines , 3-Diamines
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters