Title of article
Enantiopure tetrahydroisoquinolines via N-sulfinyl Pictet–Spengler reactions
Author/Authors
Gremmen، نويسنده , , Christiaan and Wanner، نويسنده , , Martin J and Koomen، نويسنده , , Gerrit-Jan، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
4
From page
8885
To page
8888
Abstract
Asymmetric Pictet–Spengler reactions with (R)-N-p-tolylsulfinyl-3,4-dimethoxyphenylethyl amine proceeded with high diastereoselectivity. Starting from the commercially available (R)- and (S)-Andersen reagents a highly efficient route to (+)- and (−)-salsolidine and related tetrahydroisoquinolines was developed.
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1648666
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